Endocrine Abstracts

Propylthiouracil (PTU), used to treat thyroid dysfunctions such as Graves’ disease, rarely induces lupus-like syndrome. A 52-year-old woman developed dermatological findings of systemic lupus erythematosus with malar rash, photosensitivity and discoid lupus erythematosus-like lesions, after 3 weeks of exposure to the drug. ANA and anti-dsDNA were positive. Skin biopsy of face revealed vacuolar changes in basal layer and lymphoid infiltration in perivascular region of derm...